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Amit R Agarwal

Senior Product Manager, Information Technology and Services

Hi I'm Amit R Agarwal. I am an experienced Product Manager in the life sciences domain for AI based products.

Amit R Agarwal's Bio:

Amit R Agarwal is an experienced Product Leader with over ten years in the pharmaceutical industry. He is skilled in using AI for things like predicting clinical trial outcomes, finding new drug targets, and designing drugs. Amit R Agarwal has a strong history of leading teams to success. He helped get €15 million in funding for a product ahead of time. He also guided 10 development teams, which helped automate 60% of manual tasks. He made project deliveries 45% faster, cutting an 8-week process down to 4 weeks. Amit R Agarwal's work includes creating a clinical trial prediction model that is doing 5% better than others in the industry. He also developed an AI model to find drugs that could be used in new ways, like through inhalation. He made the antibody engineering process much faster, from 6 weeks to 1 week. He also helped identify and check over 60,000 possible drug assets for buying and selling. As a Product Manager, Amit R Agarwal automated an AI process for finding new drug targets, and this work was published in a Nature journal. He also mentored three junior product managers, two of whom were promoted quickly. His work helped bring in over €10 million in yearly revenue. He also has four US patents for his innovations. Earlier in his career, Amit R Agarwal set up a molecular biology lab and did research that brought in a lot of grant money. He also completed a clinical trial as the main researcher. He has a PhD in Molecular Pharmacology and Toxicology, and Master's degrees in Regulatory Science and Pharmaceutical Science, all from the University of Southern California. He also has a Bachelor's degree in Pharmacy from the University of Pune. His skills include product development, life sciences consulting, molecular biology, and regulatory work.

Amit R Agarwal's Experience:

  • Senior Product Manager at Innoplexus

    January 2024 - Present | Pune, India

  • Product Manager at Innoplexus

    June 2020 - December 2023 | Pune, India

    Automated an artificial intelligence pipeline for novel target identification for any given indication utilising multiple target characteristics like druggability, clinical suitability, biomarker potential and gene and protein expression combined with literature evidence support and genomics analysis. Performed target identification, validation, indication prioritisation and drug combination analysis for multiple pharmaceutical clients in partnership for asset development using the product. Performed ontology fixes to increase data coverage and supported the data science and data engineering teams with validation. Identified potential targets for a small biotech client and the asset is currently in clinical development.

  • Research Scientist and HOD Molecular Biology at Chest Research Foundation

    September 2015 - December 2020 | Pune, India

    Set-up the molecular biology laboratory with state-of-the-art facilities and showed a metabolic impairment in systemic immune cells from patients with chronic obstructive pulmonary disease (COPD) Applied for a patent for a diagnostic blood test to distinguish between asthma and COPD Started and conducted seven workshops on Cell-culture applications, techniques and hands-on training (CURATOR)

  • IRB Consultant at IRB Company

    March 2014 - August 2015 | Buena Park, CA

    Coordinate day to day operations of the IRB in collaboration with IRB manager, IRB coordinator and Medical Director. Evaluate IRB applications for completeness and conformance to regulations, guidelines and best practices. Alerts IRB Manager, Chair and Medical Director to protocol issues that may need closer review. Work with IRB manager and other staff members, IRB Chair and Medical Director, to prepare annual accreditation reports to maintain accreditation. Ensure IRB roster is compliant with OHRP and FDA requirements.

  • Student tech-in-charge at USC School of Pharmacy

    February 2012 - October 2013

    Assist with technical training and applications for Biorad Chemidoc XRS+ imaging system in the Translational Research Laboratory at USC School of Pharmacy

  • Summer intern at Abbott Medical Optics

    May 2009 - August 2009

    o Brought an outsourced test in-house by setting-up the direct contact test for cytotoxicity of multi purpose solutions. o A critical study which helped in the marketing approval of RevitaLens OcuTec(R) Multi-Purpose Disinfecting Solution was presented at ARVO in 2010. o Also referenced in product scientific literature at http://www.amo-inc.com/products/corneal/multi-purpose-solution/revitalens-ocutec-multi-purpose-disinfecting-solution

  • Graduate Trainee at Twilight Litaka Pharma Ltd, India

    October 2006 - November 2006

    Analyzed Batch manufacturing processes for Quality Control of tablets and documented the study and observations to suggest improvements

  • PhD canditate at University of Southern California

    August 2008

    As a Research Assistant in Prof. Enrique Cadenas' laboratory my thesis focuses on understanding the effect of cigarette smoke on lung mitochondrial function in order to gain insights on the factors forming the molecular basis of disease (COPD). Some of the highlights of my accomplishments include: o Conceptualized the reason for pulmonary surfactant deficiency in smokers to be due to a metabolic shift in lung alveolar cell mitochondrion o Exposed mice to cigarette smoke using Teague smoke exposure system and designed experiments to prove the concept o Isolated mitochondrion and primary type II alveolar cells from mice lungs exposed to cigarette smoke o Performed enzymatic assays and various cell biology techniques on biological samples o Experience with cancerous cell lines from human and rat origin o Proficiency with Seahorse XF Extracellular Flux Analyzer to assess mitochondrial function o Performed statistical analyses such as Students t-test and ANNOVA on results obtained

Amit R Agarwal's Education:

  • University of Southern California

    2010 – 2013
    PhD
    Concentration: Molecular Pharmacology and Toxicology

  • University of Southern California

    2010 – 2013
    MS
    Concentration: Regulatory Science

  • University of Southern California

    2008 – 2010
    MS
    Concentration: Pharmaceutical Sciences

  • University of Pune

    2005 – 2008
    Bachelor of Pharmacy
    Concentration: Pharmacy

  • Sinhgad College of Pharmacy (Poly)

    2003 – 2005
    Diploma in Pharmacy
    Concentration: Pharmacy

Amit R Agarwal's Interests & Activities:

Drug Discovery, Target Identification, Clinical Trials, Artificial Intelligence (AI), Product Management




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